A plane carrying 16 people has disappeared over eastern Indonesia, an airline official said.
The Twin Otter plane was on a commercial flight over the remote Papua region when it lost contact with ground officials, said Captain Nikmatullah, the director of operations of airline Merpati Nusantara.
No trace had been found of the plane more than four hours after it took off, said Captain Nikmatullah.
The aircraft was carrying enough fuel to keep it in the air for 3.5 hours, he said.
The plane was on a 50-minute journey from Sentani, a major airport in Papua, to the town of Oksibil, he said.
Much of Papua is covered with impenetrable jungles and mountains. In the past, crashed planes have never been found.
Indonesia, a nation of more than 18,000 islands, has seen several major air crashes in recent years which have killed more than 220.
In 2007, the European Union banned all Indonesian carriers from landing. It recently lifted the ban on four of them, including Garuda, the country's flag carrier, saying standards had improved.
