A paramedic sent to Michael Jackson's mansion said he saw the doctor charged in the singer's death scoop up three bottles of lidocaine from the floor and place the vials in a bag during efforts to revive the pop star.
Paramedic Martin Blount testified he was surprised to see the bottles because Dr Conrad Murray had told paramedics he hadn't given Jackson any drugs.
He says Murray also produced a hypodermic needle at one point and wanted to use it on the singer. Mr Blount said he and fellow paramedics refused.
The medic is the seventh witness called at a multi-day preliminary hearing after which a judge will determine whether there is enough evidence for Murray to stand trial for involuntary manslaughter. The Houston-based cardiologist has pleaded not guilty.
On Wednesday, Jackson's friend and choreographer Kenny Ortega described how the singer appeared sick during a rehearsal six days before his death and left early. The rehearsals were for a series of planned comeback concerts in London.
Mr Ortega said after that incident, Murray "was upset that I had sent Michael home the night before and didn't allow him to rehearse".
The hearing, attended by international media and fans, provided another glimpse into the private life of Jackson, a one-time superstar who grew reclusive after his acquittal on child molestation charges in 2005.
Murray was providing Jackson propofol roughly six times a week since being hired as the singer's personal physician in May 2009, Mr Walgren said.
Another bodyguard, Faheem Muhammad, testified that he saw Jackson lying on his bed. He described Murray as panicked and said the doctor asked whether anyone knew CPR.
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The hearing was expected to include testimony from police, coroner's officials and forensic experts who will describe the mix of sedatives found in Jackson's system. Preliminary hearings have a lower burden of proof than trials, and defence attorneys rarely present a case. Murray's attorney, Ed Chernoff, did not make an opening statement.
