Prominent Labour Brexiteer MP Kate Hoey has announced she will stand down at the next election.
The former minister tweeted a letter to her constituents saying that, after 30 years representing the Vauxhall constituency, she would "not seek re-election as a Labour candidate".
Labour's Stephen Pound, who represents Ealing North, and Stephen Twigg, who represents Liverpool, West Derby, have also announced that they will not stand at the next general election.
The deadline for the party's MPs to declare whether they intend to stand for re-selection as a candidate is on Monday.
Ms Hoey wrote: "Until the next general election I will of course continue every single day to give my all to help constituents in Vauxhall and to campaign for policies that make life better for residents.
"I will carry on until a general election serving with the energy, honesty and integrity that I have tried to bring to public service my whole life.
"It remains a huge privilege to serve this special part of London. I have had wonderful staff over the years some with me for over 20 years and I thank them all for their personal support.
"I am profoundly grateful to those party members, local residents, community groups and trade unions with whom I have worked and campaigned over so many years."
Ms Hoey has been MP for Vauxhall since 1989 and famously campaigned alongside Nigel Farage in favour of leaving the EU.
Last year Labour chiefs passed a vote of no confidence in Ms Hoey and called for her to be barred from standing as the Labour candidate at the next election
It came as she sided with the Government to avoid it being defeated on its Trade Bill in a Brexit showdown.
They passed a motion accusing Ms Hoey of “collaborating” with the Right-wing European Research Group, led by Jacob Rees-Mogg, in the bust-up over a customs union.
The Borough of Lambeth, which includes the Vauxhall constituency, voted 78.6 per cent to stay in the European Union in the 2016 referendum - the highest proportion of Remain voters of any area aside from Gibraltar.
